Case Studies on Second-Generation Anticoagulant Rodenticide Toxicities in Nontarget Species

Field evaluation of difethialone, a new second generation anticoagulant rodenticide in the rice fields.

A new second generation anticoagulant rodenticide, difethialone (0.0025%), was evaluated in the rice fields at three different cropping stages, viz. Milky, Panicle formation and Panicle maturation, during Kuruvai and Thaladi seasons. The difethailone (0.0025%) yielded satisfactory control success suggesting a great potential as a rodenticide especially in the early stages of rice.

New Potential Diagnostic Methods for Identifying Anticoagulant Rodenticide Poisoning in Dogs and Other Nontarget Animals

difethialone, a new second-generation anticoagulant rodenticide to Bam owl, Tyto alba Hartert under captivity

Secondary toxcity of difethialone to Barn owl (Tyto alba) has been investigated. Difethialone was fed to owls for successive periods of 1 (phase 1), 3 (phase 2) and 6 (phase 3) days viarodenticide dosed rats. The owls survived after the treament of rodenticide on phase 1 and phase 2 experiments but they died during phase 3 experiment. The results suggest that the difethialone could cause more s...

Anticoagulant Rodenticide Intoxication in Animals - A Review

The newest measures for the control of harmful rodent populations are from the anticoagulant rodenticide group, which are divided into 2 subgroups: first and second generations, and indandione derivatives. Non-target organisms are potentially at risk of direct consumption of baits (primary hazard) and of eating poisoned rodents (secondary hazard). Anticoagulant rodenticides inhibit the enzyme v...

Resistance to the Second-generation Anticoagulant Rodenticides

The second-generation anticoagulants, difenacoum, bromadiolone and brodifacoum, have taken over a considerable part of the rodenticidal market during the last six to eight years. This is partly due to the higher efficiency against a larger spectrum of rodent pest species and partly to the increasing problem of physiological resistance to the older anticoagulants. Resistance of practical importa...